polysorbate 65

overview
Product Name: Polysorbate 65
Common Name: Tween 65 / Polyoxyethylene (20) sorbitan tristearate
CAS Number: 9005-71-4
EINECS Number: 215-666-9
Molecular Formula: C₁₀₀H₁₉₄O₂₈
Molecular Weight: ~1844.6 g/mol

Polysorbate 65 is a non-ionic food-grade emulsifier produced through the ethoxylation of sorbitan tristearate, combining stearic acid, sorbitan, and ethylene oxide. It possesses a moderate-to-high degree of ethoxylation, which enhances its hydrophilicity while conserving emulsifying efficacy. Polysorbate 65 efficiently forms stable oil-in-water (O/W) emulsions, reducing interfacial tension and facilitating dispersion of lipids in aqueous systems. Its emulsifying capacity and compatibility with other emulsifiers makes it particularly useful in emulsified food formulations.

Molecular structure description
The molecular architecture of Polysorbate 65 comprises:
  • A hydrophilic polyoxyethylene chain, introduced through ethylene oxide units, enhancing water affinity.
  • A hydrophobic component formed by three stearic acid residues esterified to a sorbitan core (sorbitol-derived dehydrated ring), providing lipophilicity.
  • A sorbitan backbone, linking the hydrophobic and hydrophilic segments.

This amphiphilic structure allows Polysorbate 65 to adsorb at the oil–water interface, effectively lowering surface tension and stabilizing emulsions — enabling it to act as a reliable O/W emulsifier.

Specifications

Polysorbate 65 typically appears as a waxy, somewhat viscous liquid or semi-solid. It exhibits higher hydrophilicity than less-ethoxylated polysorbates due to its greater EO content, which translates into stronger water solubility and emulsifying strength. Its elevated HLB value makes it suitable for stabilizing emulsions rich in water phase while maintaining compatibility with less hydrophilic emulsifiers to fine-tune formulation performance.
Test IndicatorUnitMin ValueMax Value
Saponification ValuemgKOH/g8898
Hydroxyl ValuemgKOH/g4460
Acid ValuemgKOH/g-2.0
Moisture Content%-3

Applications

Polysorbate 65 is primarily employed as an emulsifier and dispersion aid in a variety of food systems. Its application features include:
  • Emulsification: Stabilizes oil-in-water emulsions by enhancing the dispersion of fats and oils.
  • High Hydrophilicity: Due to its higher EO content and HLB, it excels in aqueous-rich systems such as beverages, dressings, dairy-based emulsions, and low-fat formulations.
  • Synergistic Emulsification: When used alongside sorbitan esters, it helps achieve a balanced HLB for optimizing emulsion stability.
  • Texture Enhancement: Improves creaminess, mouthfeel, and consistency in food emulsions.
  • Versatility: Suitable for use in margarine, sauces, creams, dairy products, and confectionery, especially where high water phase presence and stable emulsification are essential.
Emulsification Efficiency – Stable W/O Emulsions

Sorbitan esters are highly effective in forming stable water-in-oil emulsions. Ideal for margarine, creams, and ointments, they help maintain consistency and prevent separation over time.

Mild & Skin-Friendly – Ideal for Cosmetics

Widely used in lotions, creams, and makeup products, sorbitan esters are non-irritating and suitable for sensitive skin. They provide smooth textures and enhance product stability.

Food Grade & Safe – Emulsifiers for Processing

Approved for food use, they act as emulsifiers in sauces, dairy products, and spreads. Improve mouthfeel, extend shelf life, and maintain homogeneity of processed foods.

Pharmaceutical Use – Enhances Drug Stability

Used in medicinal creams, gels, and suspensions, sorbitan esters help deliver oil-soluble actives effectively. They improve bioavailability and ensure long-term formulation stability.

storage & package

Storage:
Store in a cool, dry, and well-ventilated area, away from direct sunlight and sources of heat.
Avoid contact with harmful or incompatible substances. Handle with care during transportation to prevent leakage or contamination.

Transportation:
Transport as a general chemical product, following standard safety and handling procedures.

Package:
Polysorbate 65 is packed in high-quality PE drums with double-seal lids.
Standard packaging sizes include 25kg/drum, 200kg/drum, and 1000kg IBC tote to meet different usage needs.

25 Kg /drum
200kg/drum
1000kg IBC

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