overview
Common Name: Tween 65 / Polyoxyethylene (20) sorbitan tristearate
CAS Number: 9005-71-4
EINECS Number: 500-019-9 or EC Number 500-020-4 (sources vary) :contentReference[oaicite:2]{index=2}
Molecular Formula: C₁₀₀H₁₉₄O₂₈ (or sometimes reported as ~C₃₂H₆₂O₁₀ in older listings; the higher formula reflects the full ethoxylated structure) :contentReference[oaicite:3]{index=3}
Molecular Weight: ~1844.6 g/mol :contentReference[oaicite:4]{index=4}
Polysorbate 65 (Tween 65), a nonionic surfactant formed by ethoxylating sorbitan tristearate, functions as an effective emulsifier and solubilizer in food, cosmetic, and pharmaceutical formulations. Its high hydrophilicity (higher HLB) makes it suitable for stabilizing oil-in-water emulsions with heavier or more lipophilic ingredients. Commonly applied in frozen desserts, baked goods, and liquid emulsions, Polysorbate 65 enhances texture, stability, and dispersibility in complex formulations.
Molecular structure description
Hydrophilic part: Polyoxyethylene (20) sorbitan head group
HLB value: ~15.0 (hydrophilic, ideal for oil-in-water emulsions with unsaturated oils)
Specifications
It is a nonionic surfactant composed of polyoxyethylene (20) sorbitan esterified with tristearate, giving it a balanced hydrophilic-lipophilic profile.
It is dispersible in warm water and ethanol; slightly soluble in vegetable oils; and insoluble in mineral oil.
When dispersed in water, it forms creamy emulsions. Its dual-phase compatibility makes it useful in both oil-in-water and water-in-oil formulations for food, cosmetics, and pharmaceuticals.
| Test Indicator | Unit | Min Value | Max Value |
|---|---|---|---|
| Saponification Value | mgKOH/g | 45 | 55 |
| Hydroxyl Value | mgKOH/g | 65 | 80 |
| Acid Value | mgKOH/g | - | 2 |
| Moisture Content | % | - | 3 |
| Residue on Ignition | w% | - | 0.25 |
| Oxyethylene Group | w% | 65 | 69.5 |
| Arsenic (As) | mg/kg | - | 3 |
| Lead (Pb) | mg/kg | - | 2 |
Applications
It works effectively in both oil-in-water and water-in-oil emulsions and provides creamy textures in fat-rich products.
Its balanced hydrophilic-lipophilic profile makes it versatile for mixed-phase systems.
Emulsification Efficiency – Stable W/O Emulsions
Sorbitan esters are highly effective in forming stable water-in-oil emulsions. Ideal for margarine, creams, and ointments, they help maintain consistency and prevent separation over time.
Mild & Skin-Friendly – Ideal for Cosmetics
Widely used in lotions, creams, and makeup products, sorbitan esters are non-irritating and suitable for sensitive skin. They provide smooth textures and enhance product stability.
Food Grade & Safe – Emulsifiers for Processing
Approved for food use, they act as emulsifiers in sauces, dairy products, and spreads. Improve mouthfeel, extend shelf life, and maintain homogeneity of processed foods.
Pharmaceutical Use – Enhances Drug Stability
Used in medicinal creams, gels, and suspensions, sorbitan esters help deliver oil-soluble actives effectively. They improve bioavailability and ensure long-term formulation stability.
storage & package
Storage:
Store in a cool, dry, and well-ventilated area, away from direct sunlight and sources of heat.
Avoid contact with harmful or incompatible substances. Handle with care during transportation to prevent leakage or contamination.
Transportation:
Transport as a general chemical product, following standard safety and handling procedures.
Package:
Polysorbate 65 is packed in high-quality PE drums with double-seal lids.
Standard packaging sizes include 25kg/drum, 200kg/drum, and 1000kg IBC tote to meet different usage needs.
25 Kg /drum
200kg/drum
