overview
Common Name: Tween 80 / Polyoxyethylene (20) sorbitan monooleate
CAS Number: 9005-65-6
EINECS Number: 500-019-9 (E Number: E433)
Molecular Formula: C₆₄H₁₂₄O₂₆
Molecular Weight: ~1309-1310 g/mol
Polysorbate 80 (Tween 80) is a widely used nonionic surfactant produced from the ethoxylation of sorbitan monooleate. It serves as an effective emulsifier, solubilizer, and dispersant across food, cosmetics, pharmaceuticals, and industrial formulations. Known for its versatility and gentle profile, Polysorbate 80 stabilizes oil-in-water systems, helps solubilize essential oils and fragrances, and is commonly used in injectable and oral pharmaceutical products.
Molecular structure description
Hydrophilic part: Polyoxyethylene (5) sorbitan head group
HLB value: ~10.0 (moderately hydrophilic, suited for emulsions requiring more oil-phase compatibility)
Specifications
It is a nonionic surfactant composed of polyoxyethylene (20) sorbitan esterified with oleic acid, producing an amphiphilic molecule ideal for emulsifying unsaturated oils.
It is soluble in water, ethanol, and ethyl acetate; slightly soluble in vegetable oils; and insoluble in mineral oil.
When dispersed in water, it forms clear to slightly opalescent solutions. Its strong oil-in-water emulsifying capacity and stability in a wide pH range make it popular in food, cosmetics, and pharmaceuticals.
| Test Parameter | Unit | Min Value | Max Value | Specification Range |
|---|---|---|---|---|
| Saponification Value | mgKOH/g | 95 | 115 | 95-115 |
| Hydroxyl Value | mgKOH/g | 165 | 195 | 165-195 |
| Acid Value | mgKOH/g | - | 3 | ≤3 |
| Moisture Content | % | - | 3 | ≤3 |
Applications
It is especially effective with unsaturated oils, making it valuable in oil-in-water emulsions containing vegetable oils and essential oils.
Its stability in a broad pH and temperature range enhances formulation performance.
Emulsification Efficiency – Stable W/O Emulsions
Sorbitan esters are highly effective in forming stable water-in-oil emulsions. Ideal for margarine, creams, and ointments, they help maintain consistency and prevent separation over time.
Mild & Skin-Friendly – Ideal for Cosmetics
Widely used in lotions, creams, and makeup products, sorbitan esters are non-irritating and suitable for sensitive skin. They provide smooth textures and enhance product stability.
Food Grade & Safe – Emulsifiers for Processing
Approved for food use, they act as emulsifiers in sauces, dairy products, and spreads. Improve mouthfeel, extend shelf life, and maintain homogeneity of processed foods.
Pharmaceutical Use – Enhances Drug Stability
Used in medicinal creams, gels, and suspensions, sorbitan esters help deliver oil-soluble actives effectively. They improve bioavailability and ensure long-term formulation stability.
storage & package
Storage:
Store in a cool, dry, and well-ventilated area, away from direct sunlight and sources of heat.
Avoid contact with harmful or incompatible substances. Handle with care during transportation to prevent leakage or contamination.
Transportation:
Transport as a general chemical product, following standard safety and handling procedures.
Package:
Polysorbate 80 is packed in high-quality PE drums with double-seal lids.
Standard packaging sizes include 25kg/drum, 200kg/drum, and 1000kg IBC tote to meet different usage needs.
25 Kg /drum
200kg/drum
